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cytonome hydris front view

Cytonome Hydris™

Industrial-Scale Cell Purification System

Introducing the Hydris™ high throughput cell purification system. Using the power of parallel technology and advanced automation to improve the efficiency of routine and repetitive cell sorting tasks.

Download Product Sheet

Overview

Building on the proven design and worldwide operational experience of the Cytonome Genesis III™ platform, the Cytonome Hydris™ system leverages the power of full-scale, high-throughput cell sorting by means of parallel architecture with optimized droplet sorting technology. The Cytonome Hydris™ system can leverage custom, application-specific designs with independent sort head monitoring for ease-of-use. The innovative design provides increased efficiency and productivity benefits and thus can contribute significantly to lean manufacturing.

hydris features close view angle

Features

  • Up to three (3) sort head assemblies running in parallel
  • Individually dedicated sort head performance monitoring
  • Jet-in-air droplet sorting reliability
  • Optical and laser upgrade paths
  • Optional biohazard containment module(s)
  • Automated control systems
cytonome hydris benefits diagram technology

Benefits

  • High throughput combined sort speeds
  • Sorting efficiency and reliability
  • Proven performance, reliability
  • Flexibility in sorting applications
  • Safety for lab personnel
  • Walk-away sorting

Cytonome Hydris™ Product Specifications

Cell Types

  • Mammalian
  • Additional cell types possible (i.e. yeast, bacteria)

Sample Concentration

  • 1,000 to 100 million cells per ml (cell type dependent)

Sample Flow Rate

  • 4 ml per hour (three 12 x 75mm tubes as input)

Cell Measurement Parameters

  • Light scatter, Phycoerythrin (PE) emission (standard)
  • Additional fluorescence wavelengths possible

Cell Analysis Rate

  • Up to 1 billion cells per hour

Cell Purification Rate

  • Up to 300 million cells per hour (depending upon your application)

Sort Collection Vessels

  • 1.5 ml, 5 ml, 15 ml, 50 ml tubes; cell culture flasks
  • Other collection devices possible

Sort Purity

  • >99%

Biohazard Containment

  • Optional biological safety cabinet and aerosol evacuation systems

Sort Technology

  • Microdroplet sorting

Flow Cell Type

  • Ceramic tip, 70 micron orifice (standard)
  • Optional disposable polymer tips

Laser Wavelength

  • 488 nm (blue) (standard)
  • Additional laser wavelengths available

Optical Detection

  • Photomultipliers

Sensitivity

  • < 250 molecules of equivalent fluorescein

Signal Dynamic Range

  • 1 to 50,000 (4.5 orders of magnitude)

Connectivity

  • Ethernet
  • Additional remote display monitor (HDMI, touch)

User Alerts

  • Sort status, run errors

Dimensions

  • 122 cm x 89 cm x 204 cm (48 in x 35 in x 80 in)

Facility Requirements

  • Single 110/240V AC outlet, compressed gas, vacuum